The RING finger protein family in health and disease
Abstract Ubiquitination is a highly conserved and fundamental posttranslational modification (PTM) in all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) finger (RNF) protein, containing the RING domain, exerts E3 ubiquitin ligase that mediates the covalent attach...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-08-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-022-01152-2 |