Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis

Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis

Maresin1 (MaR1) is an endogenous pro-resolving lipid mediator produced from polyunsaturated fatty acids and is believed to have antioxidant and anti-inflammatory properties. The objective of this study was to estimate MaR1′s impact on type 2 diabetic osteoporosis (T2DOP) and its pharmacological mode...

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Bibliographic Details
Main Authors: Zhanwei Zhang, Chonghao Ji, Ya-Nan Wang, Shiyue Liu, Maoshan Wang, Xin Xu, Dongjiao Zhang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
maresin1
diabetic osteoporosis
NRF2
ferroptosis
glutathione peroxidase 4
Online Access:https://www.mdpi.com/2073-4409/11/16/2560

Internet

https://www.mdpi.com/2073-4409/11/16/2560

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