Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Summary: Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular cells embedded in collagen hydrogel that allows investigation of pathogen interactions with the endot...

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Bibliographic Details
Main Authors: Sophia Schönherr-Hellec, Eirini Chatzopoulou, Jean-Philippe Barnier, Yoann Atlas, Sébastien Dupichaud, Thomas Guilbert, Yves Dupraz, Julie Meyer, Catherine Chaussain, Caroline Gorin, Xavier Nassif, Stephane Germain, Laurent Muller, Mathieu Coureuil
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Biological sciences
Microbiology
Bioengineering
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003632

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http://www.sciencedirect.com/science/article/pii/S2589004223003632

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