Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Summary: Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular cells embedded in collagen hydrogel that allows investigation of pathogen interactions with the endot...

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Hlavní autoři: Sophia Schönherr-Hellec, Eirini Chatzopoulou, Jean-Philippe Barnier, Yoann Atlas, Sébastien Dupichaud, Thomas Guilbert, Yves Dupraz, Julie Meyer, Catherine Chaussain, Caroline Gorin, Xavier Nassif, Stephane Germain, Laurent Muller, Mathieu Coureuil
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2023-04-01
Edice:iScience
Témata:
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2589004223003632