A tissue specific-infection mouse model of SARS-CoV-2

Abstract Animal models play crucial roles in the rapid development of vaccines/drugs for the prevention and therapy of COVID-19, but current models have some deficits when studying the pathogenesis of SARS-CoV-2 on some special tissues or organs. Here, we generated a human ACE2 and SARS-CoV-2 NF/F k...

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Bibliographic Details
Main Authors: Bo Yang, Chao Liu, Xiaohui Ju, Bingbing Wu, Zhuangfei Wang, Fucheng Dong, Yanying Yu, Xiaohui Hou, Min Fang, Fei Gao, Xuejiang Guo, Yaoting Gui, Qiang Ding, Wei Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00536-0