Physioxia Has a Beneficial Effect on Cartilage Matrix Production in Interleukin-1 Beta-Inhibited Mesenchymal Stem Cell Chondrogenesis

Physioxia Has a Beneficial Effect on Cartilage Matrix Production in Interleukin-1 Beta-Inhibited Mesenchymal Stem Cell Chondrogenesis

Osteoarthritis (OA) is a degenerative condition that involves the production of inflammatory cytokines (e.g., interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6)) that stimulate degradative enzymes, matrix metalloproteinases (MMPs) and agg...

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Bibliographic Details
Main Authors: Girish Pattappa, Ruth Schewior, Isabelle Hofmeister, Jennifer Seja, Johannes Zellner, Brian Johnstone, Denitsa Docheva, Peter Angele
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
cartilage
mesenchymal stem cells
chondrogenesis
hypoxia
interleukin-1β
early osteoarthritis
Online Access:https://www.mdpi.com/2073-4409/8/8/936

Internet

https://www.mdpi.com/2073-4409/8/8/936

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