Tertiary lymphoid structures predict survival and response to neoadjuvant therapy in locally advanced rectal cancer

Abstract Tertiary lymphoid structure (TLS) contributes to the anti-tumor immune response, and predicts the prognosis of colorectal cancer patients. However, the potential impact of TLS in shaping the immune status of rectal adenocarcinoma, and the intrinsic relationship between TLS and neoadjuvant t...

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Bibliographic Details
Main Authors: Qianyu Wang, Wentao Zhong, Xiaofei Shen, Zechen Hao, Meng Wan, Xiaopeng Yang, Ran An, Hongyan Zhu, Huiyun Cai, Tao Li, Yuan Lv, Xing Dong, Gang Chen, Aijun Liu, Junfeng Du
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00533-w