Abnormal placental development and early embryonic lethality in EpCAM-null mice.

EpCAM (CD326) is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential tumor marker an...

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Bibliographic Details
Main Authors: Keisuke Nagao, Jianjian Zhu, Mallorie B Heneghan, Jeffrey C Hanson, Maria I Morasso, Lino Tessarollo, Susan Mackem, Mark C Udey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2796178?pdf=render