Functional Irreplaceability of Escherichia coli and Shewanella oneidensis OxyRs Is Critically Determined by Intrinsic Differences in Oligomerization

Functional Irreplaceability of Escherichia coli and Shewanella oneidensis OxyRs Is Critically Determined by Intrinsic Differences in Oligomerization

ABSTRACT LysR-type transcriptional regulators (LTTRs), which function in diverse biological processes in prokaryotes, are composed of a conserved structure with an N-terminal DNA-binding domain (DBD) and a C-terminal signal-sensing regulatory domain (RD). LTTRs that sense and respond to the same sig...

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Bibliographic Details
Main Authors: Weining Sun, Yanlin Fan, Fen Wan, Yizhi J. Tao, Haichun Gao
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
transcription regulation
oxidative stress response
OxyR
Gram-negative bacteria
protein structure
protein structure-function
Online Access:https://journals.asm.org/doi/10.1128/mbio.03497-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03497-21

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