Small‐molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual‐inhibiting properties for bladder cancer treatment

Small‐molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual‐inhibiting properties for bladder cancer treatment

Abstract Bladder cancer (BCa) is one of the most common malignancies worldwide. Although multiple efforts have been made, the 5‐year survival rate of patients with BCa remains unchanged in recent years. Overexpression of the epidermal growth factor receptor (EGFR) is found in ≈74% of BCa tissue spec...

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Bibliographic Details
Main Authors: Guoyin Li, Zewen Song, Yi Ru, Jing Zhang, Lianxiang Luo, Wei Yang, Hao Wu, Haibao Jin, Xuanwen Bao, Di Wei, Zhao Yan, Haijing Qu, Zheng Zhu, Xiangdong Xue, Gang Zhou
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Exploration
Subjects:
bladder cancer
epidermal growth factor receptor (EGFR)
hesperidin
high drug loading
triptolide
Online Access:https://doi.org/10.1002/EXP.20220141

Internet

https://doi.org/10.1002/EXP.20220141

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