Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

Descrizione completa

Dettagli Bibliografici
Autori principali: James A Stapleton, Jeongwoon Kim, John P Hamilton, Ming Wu, Luiz C Irber, Rohan Maddamsetti, Bryan Briney, Linsey Newton, Dennis R Burton, C Titus Brown, Christina Chan, C Robin Buell, Timothy A Whitehead
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4720449?pdf=render

Accesso online

http://europepmc.org/articles/PMC4720449?pdf=render

Documenti analoghi