Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

Full description

Bibliographic Details
Main Authors: James A Stapleton, Jeongwoon Kim, John P Hamilton, Ming Wu, Luiz C Irber, Rohan Maddamsetti, Bryan Briney, Linsey Newton, Dennis R Burton, C Titus Brown, Christina Chan, C Robin Buell, Timothy A Whitehead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4720449?pdf=render

Internet

http://europepmc.org/articles/PMC4720449?pdf=render

Similar Items