Identification of Tumor Antigens and Immune Subtypes of Esophageal Squamous Cell Carcinoma for mRNA Vaccine Development

Identification of Tumor Antigens and Immune Subtypes of Esophageal Squamous Cell Carcinoma for mRNA Vaccine Development

Purpose: The applicability of mRNA vaccines against esophageal squamous cell carcinoma (ESCC) remains unclear. Here, we identified potential antigens for developing mRNA vaccines against ESCC and characterized immune subtypes to select appropriate patients for vaccination.Methods: RNA-seq, genetic a...

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Bibliographic Details
Main Authors: Tong Lu, Ran Xu, Cheng-Hao Wang, Jia-Ying Zhao, Bo Peng, Jun Wang, Lin-You Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
esophageal squamous cell carcinoma (ESCC)
immune landscape
immune subtype
mRNA vaccine
tumor antigens
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.853113/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.853113/full

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