GLP-1 receptor agonist exenatide restores atypical antipsychotic clozapine treatment-associated glucose dysregulation and damage of pancreatic islet beta cells in mice

Background and aims: The aim of this study was to investigate the effect of a glucagon-like peptide-1 receptor agonist (GLP-1RA), exenatide, on clozapine-associated glucose dysregulation in mice. Materials and methods: We randomly separated B6 male mice into four groups (A to D). Mice in groups C an...

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Bibliographic Details
Main Authors: Brend Ray-Sea Hsu, Shin-Huei Fu
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750016300361