A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models

A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models

Background: TLRs are some of the actively pursued drug-targets in immune disorders. Owing to a recent surge in the cognizance of TLR structural biology and signalling pathways, numerous therapeutic modulators, ranging from low-molecular-weight organic compounds to polypeptides and nucleic acid agent...

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Bibliographic Details
Main Authors: Asma Achek, Hyuk-Kwon Kwon, Mahesh Chandra Patra, Masaud Shah, Riwon Hong, Wang Hee Lee, Wook-Young Baek, Yang Seon Choi, Gi-Young Kim, Thuong L.H. Pham, Chang-Hee Suh, Wook Kim, Dae-Hyun Hahm, Sangdun Choi
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300207

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http://www.sciencedirect.com/science/article/pii/S2352396420300207

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