High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome

High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome

Abstract Background Polycystic ovary syndrome (PCOS) is one of the most complex endocrine disorders in women of reproductive age. Abnormal proliferation of granulosa cells (GCs) is an important cause of PCOS. This study aimed to explore the role of fatty acid-binding protein 5 (FABP5) in granulosa c...

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Bibliographic Details
Main Authors: Jingyu Liu, Jie Li, Xin Wu, Mei Zhang, Guijun Yan, Haixiang Sun, Dong Li
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Ovarian Research
Subjects:
PCOS
FABP5
Granulosa cell
Proliferation
Fatty acid synthesis
PI3K-AKT
Online Access:https://doi.org/10.1186/s13048-024-01368-6

Internet

https://doi.org/10.1186/s13048-024-01368-6

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