Assessment of Antidiabetic Activity of the Shikonin by Allosteric Inhibition of Protein-Tyrosine Phosphatase 1B (PTP1B) Using State of Art: An In Silico and In Vitro Tactics

Assessment of Antidiabetic Activity of the Shikonin by Allosteric Inhibition of Protein-Tyrosine Phosphatase 1B (PTP1B) Using State of Art: An In Silico and In Vitro Tactics

<i>Diabetes mellitus</i> is a multifactorial disease that affects both developing and developed countries and is a major public health concern. Many synthetic drugs are available in the market, which counteracts the associated pathologies. However, due to the propensity of side effects,...

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Bibliographic Details
Main Authors: Mohd Saeed, Ambreen Shoaib, Munazzah Tasleem, Nadiyah M. Alabdallah, Md Jahoor Alam, Zeina El Asmar, Qazi Mohammad Sajid Jamal, Fevzi Bardakci, Saad S. Alqahtani, Irfan Ahmad Ansari, Riadh Badraoui
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
diabetes mellitus
protein-tyrosine phosphatase
shikonin
hypoglycemic
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/13/3996

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https://www.mdpi.com/1420-3049/26/13/3996

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