Furin as a therapeutic target in cystic fibrosis airways disease

Clinical management of cystic fibrosis (CF) has been greatly improved by the development of small molecule modulators of the CF transmembrane conductance regulator (CFTR). These drugs help to address some of the basic genetic defects of CFTR; however, no suitable CFTR modulators exist for 10% of peo...

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Bibliographic Details
Main Authors: Lisa E.J. Douglas, James A. Reihill, Bethany M. Montgomery, S. Lorraine Martin
Format: Article
Language:English
Published: European Respiratory Society 2023-05-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/32/168/220256.full