Association of transforming growth factor (TGF) p1 T(861-20)C polymorphism with bone mineral density and TGFip gene expression in postmenopausal osteoporosis

Association of transforming growth factor (TGF) p1 T(861-20)C polymorphism with bone mineral density and TGFip gene expression in postmenopausal osteoporosis

Objective: to study the mechanism for the involvement of ТGFβ1 T(861-20)C in bone resorption in postmenopausal osteoporosis (OP). Material and methods. DNA from 158 postmenopausal women and patients with OP and from 89 healthy age-matched women was examined by polymerase chain reaction (PCR)-restric...

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Bibliographic Details
Main Authors: Elena Vasilyevna Chetina, M Yu Krylov, N V Demin, O A Nikitinskaya, E A Korotkova, N V Toroptsova, K A Maslova, L I Benevolenskaya, V A Myakotkin
Format: Article
Language:Russian
Published: IMA PRESS LLC 2012-04-01
Series:Научно-практическая ревматология
Subjects:
postmenopausal osteoporosis
bone mineral density
single nucleotide polymorphism
transforming growth factor β1
blood gene expression in blood
Online Access:https://rsp.mediar-press.net/rsp/article/view/1167

Internet

https://rsp.mediar-press.net/rsp/article/view/1167

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