Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer

Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer

Colorectal adenocarcinomas arise from luminal lining epithelium of the colorectal tract which is covered with highly glycosylated mucins. Mucin O-glycosylation is initiated by a family of polypeptide N-acteylgalactosaminyltransferases (GALNTs). This study examined GALNT6 protein expression in 679 co...

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Bibliographic Details
Main Authors: Makiko Ogawa, Atsushi Tanaka, Kei Namba, Jinru Shia, Julia Y. Wang, Michael H. Roehrl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
GALNT6
glycosylation
colorectal cancer
early stage
risk prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.802548/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.802548/full

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