Heavy Alcohol Exposure Activates Astroglial Hemichannels and Pannexons in the Hippocampus of Adolescent Rats: Effects on Neuroinflammation and Astrocyte Arborization

Heavy Alcohol Exposure Activates Astroglial Hemichannels and Pannexons in the Hippocampus of Adolescent Rats: Effects on Neuroinflammation and Astrocyte Arborization

A mounting body of evidence indicates that adolescents are specially more susceptible to alcohol influence than adults. However, the mechanisms underlying this phenomenon remain poorly understood. Astrocyte-mediated gliotransmission is crucial for hippocampal plasticity and recently, the opening of...

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Bibliographic Details
Main Authors: Gonzalo I. Gómez, Romina V. Falcon, Carola J. Maturana, Valeria C. Labra, Nicole Salgado, Consuelo A. Rojas, Juan E. Oyarzun, Waldo Cerpa, Rodrigo A. Quintanilla, Juan A. Orellana
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
alcoholism
glia
connexins
pannexins
astrocyte
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00472/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00472/full

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