E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism

E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism

ObjectiveGut microbiota and its metabolites have regulatory effects on PCOS related ovarian dysfunction and insulin resistance. Escherichia coli Nissle 1917 (EcN) is a genetically controlled probiotic with an excellent human safety record for improving gut microbiome metabolic disorders and immune s...

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Bibliographic Details
Main Authors: Man Luo, Yuanyuan Chen, Xiangyang Pan, Hongmei Chen, Lang Fan, Yi Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
E. coli Nissle 1917
IL-22
polycystic ovary syndrome
mitochondrial injury
microbial metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1137089/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1137089/full

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