Nucleoside Analogs That Inhibit SARS-CoV-2 Replication by Blocking Interaction of Virus Polymerase with RNA

Nucleoside Analogs That Inhibit SARS-CoV-2 Replication by Blocking Interaction of Virus Polymerase with RNA

The SARS-CoV-2 betacoronavirus pandemic has claimed more than 6.5 million lives and, despite the development and use of COVID-19 vaccines, remains a major global public health problem. The development of specific drugs for the treatment of this disease remains a very urgent task. In the context of a...

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Bibliographic Details
Main Authors: Elena Matyugina, Ivan Petushkov, Sergei Surzhikov, Vasily Kezin, Anna Maslova, Olga Ivanova, Olga Smirnova, Ilya Kirillov, Irina Fedyakina, Andrey Kulbachinskiy, Sergey Kochetkov, Anastasia Khandazhinskaya
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
antiviral activity
carbocyclic and acyclic analogs of nucleosides
6-substituted derivatives of 3H-pyrrolo [2,3-d]-pyrimidine-2-one
inhibitors
SARS-CoV-2 RNA-dependent RNA polymerase
influenza virus
Online Access:https://www.mdpi.com/1422-0067/24/4/3361

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https://www.mdpi.com/1422-0067/24/4/3361

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