Chronic Administration of Cannabinoid Receptor 2 Agonist (JWH-133) Increases Ectopic Ovarian Tumor Growth and Endocannabinoids (Anandamide and 2-Arachidonoyl Glycerol) Levels in Immunocompromised SCID Female Mice

Cannabinoid-based therapies are increasingly being used by cancer patients to treat chemotherapy-induced nausea and vomiting. Recently, cannabinoids have gained increased attention for their effects on cancer growth. Indeed, the effect of CB2 (JWH-015, JWH-133) agonists on breast cancer models have...

Full description

Bibliographic Details
Main Authors: Henry L. Blanton, Melissa C. McHann, Haley De Selle, Canice Lei Dancel, Jose-Luis Redondo, Deborah Molehin, Nadezhda A. German, Scott Trasti, Kevin Pruitt, Isabel Castro-Piedras, Josée Guindon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.823132/full