Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases

Abstract Most neurodegenerative disorders are diseases of protein homeostasis, with misfolded aggregates accumulating. The neurodegenerative process is mediated by numerous metabolic pathways, most of which lead to apoptosis. In recent years, hydrophilic bile acids, particularly tauroursodeoxycholic...

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Bibliographic Details
Main Authors: Kareem Khalaf, Paolo Tornese, Antoniangela Cocco, Alberto Albanese
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-022-00307-z