Focused Ultrasound Enhances Brain Delivery of Sorafenib Nanoparticles

Focused Ultrasound Enhances Brain Delivery of Sorafenib Nanoparticles

Glioblastoma (GBM) is a universally lethal form of brain cancer. The success of novel treatments is hindered by the blood–brain barrier (BBB), which prevents most drugs from penetrating GBM tumors. Sorafenib (SFB), a proapoptotic multikinase inhibitor, has been investigated for the treatment of GBM;...

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Bibliographic Details
Main Authors: Daniel Dahis, Dana Meron Azagury, Fadi Obeid, Michelle Z. Dion, Alexander M. Cryer, Mariana Alonso Riquelme, Pere Dosta, Ariel William Abraham, Moshe Gavish, Natalie Artzi, Yosi Shamay, Haim Azhari
Format: Article
Language:English
Published: Wiley-VCH 2023-02-01
Series:Advanced NanoBiomed Research
Subjects:
blood–brain barrier (BBB)
focused ultrasound
glioblastoma
nanoparticles
sorafenib
Online Access:https://doi.org/10.1002/anbr.202200142

Internet

https://doi.org/10.1002/anbr.202200142

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