Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells

Differences in gene-wide DNA methylation of the Alzheimer’s disease (AD)-associated genes BIN1, HLA-DRB5, SORL1, SLC24A4, and ABCA7 are reported to be associated with AD in post-mortem brain samples. We investigated whether the same associations could be found in leukocytes collected pre-mortem. Usi...

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Bibliographic Details
Main Authors: Ida K Karlsson, Alexander Ploner, Yunzhang Wang, Margaret Gatz, Nancy L Pedersen, Sara Hägg
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2022.2158285