Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats

Topotecan is actively used in clinic, with its primary use being in treatment of various types of cancer. The approved administration routes are oral and intravenous. The purpose of this study was to investigate and identify pharmacokinetic profiles of different administration routes. We conducted p...

Full description

Bibliographic Details
Main Authors: Seung-Hyun Jeong, Ji-Hun Jang, Yong-Bok Lee
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/9/231