Active matrix metalloprotease-9 is associated with the collagen capsule surrounding the Madurella mycetomatis grain in mycetoma.

Madurella mycetomatis is the main causative organism of eumycetoma, a persistent, progressive granulomatous infection. After subcutaneous inoculation M. mycetomatis organizes itself in grains inside a granuloma with excessive collagen accumulation surrounding it. This could be contributing to treatm...

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Bibliographic Details
Main Authors: Kirsten Geneugelijk, Wendy Kloezen, Ahmed H Fahal, Wendy W J van de Sande
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3967957?pdf=render