Clinico-Immunological Profile of a 67-Year-Old Woman Affected by HER2-Positive Breast Cancer and Autoimmune Dermatomyositis

Clinico-Immunological Profile of a 67-Year-Old Woman Affected by HER2-Positive Breast Cancer and Autoimmune Dermatomyositis

A patient with HER2-positive early breast cancer (BC) developed dermatomyositis (DM), which disappeared after the first administration of adjuvant trastuzumab. No HER2 overexpression/amplification was observed in DM skin biopsies. Both BC and skin immune infiltrates were composed mostly of CD3+ T-ly...

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Bibliographic Details
Main Authors: Benedetta Pellegrino, Giulia Mazzaschi, Denise Madeddu, Cristina Mori, Costanza Anna Maria Lagrasta, Gabriele Missale, Federico Quaini, Antonino Musolino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
breast cancer
HER2
dermatomyositis
trastuzumab
autoimmune
cross-reactivity
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00192/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00192/full

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