The proline effect and the tryptophan immonium ion assist in de novo sequencing of adipokinetic hormones

Abstract Adipokinetic hormones (AKHs) in Arthopoda are characterized by special sequence features including limited choices of amino acid residues in certain positions, such as Trp in position 8. Over 100 different AKHs have been described, but de novo sequencing of novel peptide hormones can be a c...

Full description

Bibliographic Details
Main Authors: Simone König, Heather G. Marco, Gerd Gäde
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38056-2