Identification of a Gamma Interferon-Activated Inhibitor of Translation-Like RNA Motif at the 3′ End of the Transmissible Gastroenteritis Coronavirus Genome Modulating Innate Immune Response

Identification of a Gamma Interferon-Activated Inhibitor of Translation-Like RNA Motif at the 3′ End of the Transmissible Gastroenteritis Coronavirus Genome Modulating Innate Immune Response

ABSTRACT A 32-nucleotide (nt) RNA motif located at the 3′ end of the transmissible gastroenteritis coronavirus (TGEV) genome was found to specifically interact with the host proteins glutamyl-prolyl-tRNA synthetase (EPRS) and arginyl-tRNA synthetase (RRS). This RNA motif has high homology in sequenc...

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Bibliographic Details
Main Authors: Silvia Marquez-Jurado, Aitor Nogales, Sonia Zuñiga, Luis Enjuanes, Fernando Almazán
Format: Article
Language:English
Published: American Society for Microbiology 2015-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00105-15

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https://journals.asm.org/doi/10.1128/mBio.00105-15

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