S100A1 as a Potential Diagnostic Biomarker for Assessing Cardiotoxicity and Implications for the Chemotherapy of Certain Cancers.

This study examined the value of blood marker S100A1 in detecting cardiotoxicity induced by chemotherapy agents; trastuzumab and lapatinib, in normal rat heart. The rats were divided into three groups: control (n = 8, no treatment), T (n = 8, one time ip treatment with 10 mg/kg trastuzumab) and L (n...

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Main Authors: Ufuk Eryilmaz, Buket Demirci, Saliha Aksun, Murat Boyacioglu, Cagdas Akgullu, Tevfik Fikret Ilgenli, Hande Sultan Yalinkilinc, Mehmet Bilgen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4687715?pdf=render