Genetic Modifying Factors of Cystic Fibrosis Phenotype: A Challenge for Modern Medicine

Genetic Modifying Factors of Cystic Fibrosis Phenotype: A Challenge for Modern Medicine

Cystic fibrosis (CF) is a monogenic autosomal recessive disease caused by cystic fibrosis transmembrane conductance regulator (<i>CFTR</i>) gene mutations. CF is characterized by a high phenotypic variability present even in patients with the same genotype. This is due to the interventio...

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Bibliographic Details
Main Authors: Lăcrămioara Ionela Butnariu, Elena Țarcă, Elena Cojocaru, Cristina Rusu, Ștefana Maria Moisă, Maria-Magdalena Leon Constantin, Eusebiu Vlad Gorduza, Laura Mihaela Trandafir
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Journal of Clinical Medicine
Subjects:
cystic fibrosis
CFTR
modifier genes
phenotypic variability
GWAS
Online Access:https://www.mdpi.com/2077-0383/10/24/5821

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https://www.mdpi.com/2077-0383/10/24/5821

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