Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons.

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons.

Schistosomiasis is a neglected parasitic disease of major public health concern as it affects over 250 million people in developing countries. Currently there is no licensed vaccine available against schistosomiasis. The Schistosoma mansoni calpain protein, Sm-p80, is a leading vaccine candidate now...

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Bibliographic Details
Main Authors: Juan U Rojo, Michael W Melkus, Kameswara Rao Kottapalli, Oscar E Okiya, Justin Sudduth, Weidong Zhang, Adebayo J Molehin, Darrick Carter, Afzal A Siddiqui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5305113?pdf=render

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http://europepmc.org/articles/PMC5305113?pdf=render

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