Type I interferon subtypes differentially activate the anti-leukaemic function of natural killer cells

Type I interferon subtypes differentially activate the anti-leukaemic function of natural killer cells

Natural killer (NK) cells have an intrinsic ability to detect and eliminate leukaemic cells. Cellular therapies using cytokine-activated NK cells have emerged as promising treatments for patients with advanced leukaemia. However, not all patients respond to current NK cell therapies, and thus improv...

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Bibliographic Details
Main Authors: Samantha A. Barnes, Katherine M. Audsley, Hannah V. Newnes, Sonia Fernandez, Emma de Jong, Jason Waithman, Bree Foley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
leukemia
interferon subtypes
adoptive cell therapy
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1050718/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1050718/full

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