An in silico drug repurposing pipeline to identify drugs with the potential to inhibit SARS-CoV-2 replication

An in silico drug repurposing pipeline to identify drugs with the potential to inhibit SARS-CoV-2 replication

Background: Drug repurposing provides an opportunity to redeploy drugs, which are already tested for safety or approved for use in humans, for the treatment of diseases distinct from their primary indication. For example, the repurposing of dexamethasone and baricitinib has played a crucial role in...

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Bibliographic Details
Main Authors: Méabh MacMahon, Woochang Hwang, Soorin Yim, Eoghan MacMahon, Alexandre Abraham, Justin Barton, Mukunthan Tharmakulasingam, Paul Bilokon, Vasanthi Priyadarshini Gaddi, Namshik Han
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
COVID-19
Triamcinolone
Gallopamil
Drug repurposing
Artificial neural network
Drug mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914823002332

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http://www.sciencedirect.com/science/article/pii/S2352914823002332

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