DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes.

Measles virus (MV) is among the most infectious viruses that affect humans and is transmitted via the respiratory route. In macaques, MV primarily infects lymphocytes and dendritic cells (DCs). Little is known about the initial target cell for MV infection. Since DCs bridge the peripheral mucosal ti...

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Bibliographic Details
Main Authors: Lot de Witte, Rory D de Vries, Michiel van der Vlist, Selma Yüksel, Manja Litjens, Rik L de Swart, Teunis B H Geijtenbeek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2277461?pdf=render