Integrated analysis of single-cell and bulk RNA sequencing data reveals prognostic characteristics of lysosome-dependent cell death-related genes in osteosarcoma

Abstract Background Tumor cells exhibit a heightened susceptibility to lysosomal-dependent cell death (LCD) compared to normal cells. However, the role of LCD-related genes (LCD-RGs) in Osteosarcoma (OS) remains unelucidated. This study aimed to elucidate the role of LCD-RGs and their mechanisms in...

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Bibliographic Details
Main Authors: Yueshu Wu, Jun Yang, Gang Xu, Xiaolin Chen, Xiaochen Qu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-024-10283-5