Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study
Introduction: Coronary artery diseases (CADs) are a global health issue. In addition, several researchers have reported a correlation between serum vitamin D levels and different aspects of cardiovascular diseases. It has been reported that vitamin D can modulate atherothrombosis. Objectives: This s...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2023-03-01
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| Series: | Journal of Preventive Epidemiology |
| Subjects: | |
| Online Access: | https://jprevepi.com/PDF/jpe-8-e26181.pdf |
| _version_ | 1827796924079538176 |
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| author | Naser Aslanabadi Nader Jangioskouei Negar Jafari Azin Pakmehr Amirreza Khalaji Azam Esmailnejad Mohammadreza Moslemi Shahin Khabbazi |
| author_facet | Naser Aslanabadi Nader Jangioskouei Negar Jafari Azin Pakmehr Amirreza Khalaji Azam Esmailnejad Mohammadreza Moslemi Shahin Khabbazi |
| author_sort | Naser Aslanabadi |
| collection | DOAJ |
| description | Introduction: Coronary artery diseases (CADs) are a global health issue. In addition, several researchers have reported a correlation between serum vitamin D levels and different aspects of cardiovascular diseases. It has been reported that vitamin D can modulate atherothrombosis. Objectives: This study aimed to investigate the correlation between 25-hydroxyvitamin D and CAD severity. Patients and Methods: This is a cross-sectional study. The study sample consisted of patients undergoing elective coronary angiography. To assess 25-hydroxyvitamin D levels, fasting samples were collected from patients. Patients were included in this study based on the number of involved coronary vessels and SYNTAX classification. Results: The serum levels of 25-hydroxyvitamin D were significantly lower in the group of patients with CAD and cardiovascular disease than in the control group (P<0.001). This study showed, severe vitamin D deficiency caused significantly higher SYNTAX scores (P<0.001). Conclusion: The results of our study showed, vitamin D deficiency might have an essential relationship with the severity and incidence of CAD; however, we recommend further studies to investigate the preventing effects of vitamin D supplementation, primarily through intervention studies. |
| first_indexed | 2024-03-11T19:15:01Z |
| format | Article |
| id | doaj.art-432d12e20d134e9a8e4539eb1e729bb2 |
| institution | Directory Open Access Journal |
| issn | 2476-3934 |
| language | English |
| last_indexed | 2024-03-11T19:15:01Z |
| publishDate | 2023-03-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Preventive Epidemiology |
| spelling | doaj.art-432d12e20d134e9a8e4539eb1e729bb22023-10-09T09:02:28ZengSociety of Diabetic Nephropathy PreventionJournal of Preventive Epidemiology2476-39342023-03-0181e26181e2618110.34172/jpe.2023.26181jpe-26181Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional studyNaser Aslanabadi0Nader Jangioskouei1Negar Jafari2Azin Pakmehr3Amirreza Khalaji4Azam Esmailnejad5Mohammadreza Moslemi6Shahin Khabbazi7Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Cardiovascular Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Cardiovascular Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Internal Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Internal Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Cardiovascular Medicine, Tabriz University of Medical Sciences, Tabriz, IranKidney Research Center, Tabriz University of Medical Sciences, Tabriz, IranUrmia University of Medical Sciences, Urmia, IranIntroduction: Coronary artery diseases (CADs) are a global health issue. In addition, several researchers have reported a correlation between serum vitamin D levels and different aspects of cardiovascular diseases. It has been reported that vitamin D can modulate atherothrombosis. Objectives: This study aimed to investigate the correlation between 25-hydroxyvitamin D and CAD severity. Patients and Methods: This is a cross-sectional study. The study sample consisted of patients undergoing elective coronary angiography. To assess 25-hydroxyvitamin D levels, fasting samples were collected from patients. Patients were included in this study based on the number of involved coronary vessels and SYNTAX classification. Results: The serum levels of 25-hydroxyvitamin D were significantly lower in the group of patients with CAD and cardiovascular disease than in the control group (P<0.001). This study showed, severe vitamin D deficiency caused significantly higher SYNTAX scores (P<0.001). Conclusion: The results of our study showed, vitamin D deficiency might have an essential relationship with the severity and incidence of CAD; however, we recommend further studies to investigate the preventing effects of vitamin D supplementation, primarily through intervention studies.https://jprevepi.com/PDF/jpe-8-e26181.pdfcoronary angiographycoronary artery diseasevitamin d deficiencyatherothrombosis |
| spellingShingle | Naser Aslanabadi Nader Jangioskouei Negar Jafari Azin Pakmehr Amirreza Khalaji Azam Esmailnejad Mohammadreza Moslemi Shahin Khabbazi Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study Journal of Preventive Epidemiology coronary angiography coronary artery disease vitamin d deficiency atherothrombosis |
| title | Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study |
| title_full | Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study |
| title_fullStr | Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study |
| title_full_unstemmed | Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study |
| title_short | Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study |
| title_sort | association of serum vitamin d levels with coronary artery angiographic findings a cross sectional study |
| topic | coronary angiography coronary artery disease vitamin d deficiency atherothrombosis |
| url | https://jprevepi.com/PDF/jpe-8-e26181.pdf |
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