Ginsenoside panaxatriol reverses TNBC paclitaxel resistance by inhibiting the IRAK1/NF-κB and ERK pathways

Ginsenoside panaxatriol reverses TNBC paclitaxel resistance by inhibiting the IRAK1/NF-κB and ERK pathways

Background Paclitaxel (PTX) resistance is a major obstacle in the treatment of triple-negative breast cancer (TNBC). Previously, we have reported that interleukin-1 receptor-associated kinase 1 (IRAK1) and its downstream pathways are associated with PTX resistance in TNBC cells. In this study, we so...

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Bibliographic Details
Main Authors: Panpan Wang, Dan Song, Danhong Wan, Lingyu Li, Wenhui Mei, Xiaoyun Li, Li Han, Xiaofeng Zhu, Li Yang, Yu Cai, Ronghua Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2020-06-01
Series:PeerJ
Subjects:
TNBC
Paclitaxel resistance
IRAK1/NF-κB pathway
ERK pathway
Ginsenoside panaxatriol
Online Access:https://peerj.com/articles/9281.pdf

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https://peerj.com/articles/9281.pdf

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