Amyloid-ß-peptide reduces copper(II) to copper(I) independent of its aggregation state

Amyloid-ß-peptide reduces copper(II) to copper(I) independent of its aggregation state

Alzheimer’s disease (AD) is characterized by the deposition of amyloid b-peptide (Aß) and neuronal degeneration in brain regions involved in learning and memory. One of the leading etiologic hypotheses regarding AD is the involvement of free radical-mediated oxidative stress in neuronal degeneration...

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Bibliographic Details
Main Authors: CARLOS OPAZO, FRANCISCA H RUIZ, NIBALDO C INESTROSA
Format: Article
Language:English
Published: BMC 2000-01-01
Series:Biological Research
Subjects:
Aß peptide
amyloid fibrils
copper reduction
oxidative damage
Alzheimer’s Disease
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200012

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200012

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