Gypenosides Attenuate Pulmonary Fibrosis by Inhibiting the AKT/mTOR/c-Myc Pathway

Gypenosides Attenuate Pulmonary Fibrosis by Inhibiting the AKT/mTOR/c-Myc Pathway

Gypenosides (Gyps), the major active constituents isolated from Gynostemma pentaphyllum, possess anti-inflammatory and antioxidant activities. Previous studies have demonstrated that Gyps displayed potent ameliorative effects on liver fibrosis and renal fibrosis. In this study, we found that Gyps si...

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Bibliographic Details
Main Authors: Suqing Liu, Qingqing Yang, Binbin Dong, Chunhui Qi, Tao Yang, Ming Li, Shan He, Baojun Liu, Jinfeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
gypenosides
pulmonary fibrosis
AKT
mTOR
c-Myc
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.806312/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.806312/full

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