Deoxyamphimedine, a Pyridoacridine Alkaloid, Damages DNA via the Production of Reactive Oxygen Species

Deoxyamphimedine, a Pyridoacridine Alkaloid, Damages DNA via the Production of Reactive Oxygen Species

Marine pyridoacridines are a class of aromatic chemicals that share an 11H-pyrido[4,3,2-mn]acridine skeleton. Pyridoacridine alkaloids display diverse biological activities including cytotoxicity, fungicidal and bactericidal properties, production of reactive oxygen species (ROS) and topoisomerase i...

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Bibliographic Details
Main Authors: Chris M. Ireland, Louis R. Barrows, Cynthia D. Andjelic, Gisela P. Concepción, Deniz Tasdemir, Kathryn M. Marshall
Format: Article
Language:English
Published: MDPI AG 2009-05-01
Series:Marine Drugs
Subjects:
deoxyamphimedine
neoamphimedine
amphimedine
pyridoacridine
reactive oxygen species
Online Access:http://www.mdpi.com/1660-3397/7/2/196/

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http://www.mdpi.com/1660-3397/7/2/196/

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