Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro

Abstract Microtubules are key to multiple neuronal functions involving the transport of organelles, however, their relationship to neurotransmitter release is still unresolved. Here, we show that microtubules present in the presynaptic compartment of cholinergic autaptic synapses are dynamic. To inv...

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Bibliographic Details
Main Authors: Cecilia D. Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04779-1