Polybasic trafficking signal mediates golgi export, ER retention or ER export and retrieval based on membrane-proximity.

Trafficking of integral membrane proteins between the ER and Golgi complex, and protein sorting and trafficking between the TGN and endosomal/lysosomal compartments or plasma membranes, are dependent on cis-acting, linear amino acid sorting signals. Numerous sorting signals of this type have been id...

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Bibliographic Details
Main Authors: Hirendrasinh B Parmar, Chris Barry, Roy Duncan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979892?pdf=render