Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors

Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors

Abstract Intra-tumor heterogeneity (ITH) fosters tumor evolution, resistance to therapy, and relapse. Recently, many evidence have been accumulated on the occurrence of genetic ITH in pediatric cancers. With this study we aimed to address the downstream effects that genetic and epigenetic ITH, and t...

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Bibliografiska uppgifter
Huvudupphovsmän: Sara Ciceri, Andrea Carenzo, Maria Federica Iannó, Alessia Bertolotti, Carlo Morosi, Roberto Luksch, Filippo Spreafico, Paola Collini, Paolo Radice, Maura Massimino, Loris De Cecco, Daniela Perotti
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2022-10-01
Serie:Scientific Reports
Länkar:https://doi.org/10.1038/s41598-022-20536-6

Internet

https://doi.org/10.1038/s41598-022-20536-6

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