The Multifaceted Roles of Ku70/80

The Multifaceted Roles of Ku70/80

DNA double-strand breaks (DSBs) are accidental lesions generated by various endogenous or exogenous stresses. DSBs are also genetically programmed events during the V(D)J recombination process, meiosis, or other genome rearrangements, and they are intentionally generated to kill cancer during chemo-...

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Bibliographic Details
Main Authors: Sayma Zahid, Murielle Seif El Dahan, Florence Iehl, Paloma Fernandez-Varela, Marie-Helene Le Du, Virginie Ropars, Jean Baptiste Charbonnier
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
double-strand break
c-NHEJ
telomeres
protein-DNA interactions
DNA repair machinery
Online Access:https://www.mdpi.com/1422-0067/22/8/4134

Internet

https://www.mdpi.com/1422-0067/22/8/4134

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