Deep self-learning enables fast, high-fidelity isotropic resolution restoration for volumetric fluorescence microscopy

Abstract One intrinsic yet critical issue that troubles the field of fluorescence microscopy ever since its introduction is the unmatched resolution in the lateral and axial directions (i.e., resolution anisotropy), which severely deteriorates the quality, reconstruction, and analysis of 3D volume i...

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Bibliographic Details
Main Authors: Kefu Ning, Bolin Lu, Xiaojun Wang, Xiaoyu Zhang, Shuo Nie, Tao Jiang, Anan Li, Guoqing Fan, Xiaofeng Wang, Qingming Luo, Hui Gong, Jing Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-023-01230-2