An Integrated Approach for RNA-seq Data Normalization

Background DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data normalization is a critical step in the analysis of...

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Bibliographic Details
Main Authors: Shengping Yang, Donald E. Mercante, Kun Zhang, Zhide Fang
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S39781