An Integrated Approach for RNA-seq Data Normalization
Background DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data normalization is a critical step in the analysis of...
Main Authors: | Shengping Yang, Donald E. Mercante, Kun Zhang, Zhide Fang |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S39781 |
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